Methyl-Guard Plus provides 5-MTHF (active folate) and the active, tissue-ready forms of vitamins B2, B6, and B12 to support healthy methylation for cardiovascular, cognitive, and bone health.* Methylation is key to keeping homocysteine levels in balance, as well as for facilitating multiple biochemical processes involving neurotransmitter synthesis, detoxification, cardiovascular health, eye health, muscle health, bone health, and redox balance.* Maintaining a desirable level of homocysteine in the blood has joined healthy cholesterol and triglyceride levels as leading biomarkers for the maintenance of good cardiovascular health.* Maintaining normal homocysteine levels is also associated with the maintenance of bone, female reproductive, cognitive, and neurological health.* Methyl-Guard Plus supports methylation and healthy homocysteine levels with betaine (trimethylglycine), 5-MTHF (the active form of folate), riboflavin 5'-phosphate (the active form of vitamin B2), pyridoxal 5'-phosphate (the active form of vitamin B6), and methylcobalamin (an active form of vitamin B12).* • Heart/Vessels* • Mood*

ALLERGY WARNING This product is contraindicated in an individual with a history of hypersensitivity to any of its ingredients. PREGNANCY If pregnant, consult your health professional before using this product. INTERACTIONS 5-methyltetrahydrofolate (5-MTHF) supplementation is not recommended concurrently with methotrexate cancer therapy, as it can interfere with methotrexate's anti-neoplastic activity; however, 5-MTHF has not been shown to interfere with the anti-inflammatory activity of methotrexate. An individual taking methotrexate for psoriasis or rheumatoid arthritis can safely take a supplement containing folate.