Melatonin releases from the pineal gland, reaching its peak at night to help maintain healthy cell health throughout the body.82 Secretion of melatonin declines significantly with age, as the pineal gland becomes calcified.83 Jet lag, shift work, and poor vision can disrupt melatonin cycles. Melatonin keeps our circadian cycle in tune.87, 88 Not only does this hormone work to maintain cell health, it appears to regulate a system of self-repair and regeneration. As melatonin diminishes with age, our biological functions are impaired.