Skip to main content
††USA Functional Medicine MDs, DOs, NDs, DCs and Nutrition Professionals surveyed in 2025 for Designs for Health.Trifolamin™ lozenges provide a synergistic combination of the three bioavailable forms of vitamin B12, as methylcobalamin, hydroxycobalamin, and adenosylcobalamin, with the natural active form of folate as [6s]-5-methyltetrahydrofolate. These three forms of B12 are naturally present in foods, and can be readily converted in the body to the active intracellular forms of B12. Trifolamin™ lozenges are formulated to support healthy levels of vitamin B12. Folate is included because it is one of the most important cofactors that helps realize the benefits of optimizing B12 status. Trifolamin’s lozenge delivery system allows for optimal absorption of B12 and folate. It is best to take Trifolamin™ after a meal, and to allow the lozenge to dissolve slowly and completely in the mouth before swallowing.
Gluten free
Dairy free
Soy free
Milk free
Non-GMO


Suggested Use:
Take one lozenge per day, or as directed by your health care practitioner. Allow lozenge to dissolve slowly and completely in mouth and swallow.


Serving Size: One Lozenge

Amount Per Serving
Folate ... 680 mcg DFE
(as Quatrefolic® [6S]-5-methyltetrahydrofolate, glucosamine salt 800mcg)
Vitamin B12 ... 3,000 mcg
(as Methylcobalamin, Hydroxycobalamin and Adenosylcobalamin)

Other Ingredients: Mannitol, modified cellulose, natural orange flavor and color, citric acid, vegetable stearate, and luo han guo extract

This product does not contain gluten.

Quatrefolic® is covered by U.S. Patent No. 7, 947, 662 and is a registered trademark of Gnosis S.p.A.

NOTICE Color, size or shape may appear different between lots. Store at room temperature. Keep out of reach of children.

Trifolamin™

Designs for Health

Emerson Item Code

D04542

Vendor Item Code

TRIF60

Sign in to see pricing and more details

FREE Shipping on orders over $250.00!

Questions? Visit our Help Center or contact our support team: , Email or Call 800-654-4432

Call and Chat available

M-F 9:00 AM - 8:00 PM EST

Similar products

Ultra B12-Folate 90 capsules

Ultra B12-Folate

Designs for Health

90 capsules

Tricobalamin 60 lozenges

Tricobalamin

Designs for Health

60 lozenges

3B Complex 60 lozenges

3B Complex

Professional Health Products

60 lozenges

5-MTHF and B12 60 lozenges

5-MTHF and B12

Bioclinic Naturals

60 lozenges