Disclaimer: ††An IPSOS 2023 survey among US functional medicine practitioners, in an average month, Designs for Health is their personally most trusted practitioner supplement brand, meaning a brand that is sold by healthcare practitioners in their office. ††An Ipsos 2023 study among a random sample of 160 functional medicine practitioners including Doctor's of Osteopathic Medicine, Pharmacists, Acupuncturists, Athletic Trainers, Personal Trainers, Fitness Trainer/Coaches, Chiropractors, Integrative Medicine Specialists, Naturopathic Doctor, Homeopaths, Medical Doctors, Physical Therapists, Nurse Practitioner/Physician Assistants, Registered Nurses, Nutritionists, Massage Therapists, Occupational Therapists and Dieticians that are aware of Designs for Health and recommend supplements to their patients. Vitamin B6 is found in three forms – pyridoxine hydrochloride, pyridoxal, and pyridoxamine – all of which must be converted into activated pyridoxal-5phosphate (P-5-P) by the liver. P-5-P is the form of vitamin B6 the body ultimately uses and is necessary for a wide range of actions, including the production of GABA, the conversion of 5-HTP to serotonin, and also in the decarboxylation of L-Dopa to dopamine. It is also needed for glucose production as well as amino acid and lipid metabolism.