Designs for Health’s most advanced vitamin K2 formula that targets bone health with clinically studied bone remodeling factors (BRF).* BRF 45™ features 45 mg of vitamin K2 (as MK-4), the research-backed amount shown to promote bone health and strength, arterial health, and help discourage age- and hormone-related bone breakdown in women and men, such as during menopause and andropause.* Vitamins K1 and geranylgeraniol are also included to support conversion to vitamin K2 (as MK-4).* BRF 45™ may provide nutritional support for individuals who are at risk of bone loss, bone fracture, arterial stiffness, and other relevant conditions in which high amounts of vitamin K1 and/or vitamin K2 may be beneficial.*

At least twice a day (once first thing in the morning and another test one to two hours after a nitrate containing supplement or meal). Can be used multiple times a day for hourly or daily monitoring.