• Key factor in several key biological pathways, including methylation reactions, glutathione formation and glutathione-s-transferase activity* • Complexed with disulfate tosylate, a well-tolerated, stable and clinically tested form • Enteric coating protects SAMe degradation from gastric acid, allowing for significantly improved intestinal absorption* • 200 mg SAMe per tablet, allows for flexible dose titration • Sourced from the highest quality Italian Isoactive SAMe available on the market • Isoactive SAMe uses a natural fermentation process that yields 40% higher active ingredients over synthetic variations • Suitable for vegetarians/vegans

If you are taking anti-depressant medications, consult a health care professional prior to taking SAMe in place of or in addition to those medications. Not recommended for use in children. Do not take at night as SAMe may cause anxiety, restlessness, insomnia. People with bipolar disorder or (manic-depressive illness) should not use SAMe unless under medical supervision. Possible side effects are: mild gastrointestinal upsets (such as stomach pain, nausea, diarrhea, flatulence), anxiety, hyperactive muscle movement, insomnia and hypomania. When these side effects occur, they often diminish with time or resolve with lower doses or cessation of use. There are no documented cases of allergies to SAMe. Consult your healthcare professional prior to use if you are pregnant, trying to become pregnant, breastfeeding, taking medication, have a medical condition, or anticipate surgery. Keep out of reach of children. Sealed for your protection. Do not use if seal is broken. For freshness, store in a cool, dry place.Contains 200 mg of high quality SAMe, produced using a natural fermentation process that yields higher active ingredients over synthetic variations. Enteric coated to ensure a biologically active product.